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刘白南 副教授
2020-08-11 10:22   审核人:

刘白南,男,博士,副教授,硕士研究生导师。主要从事以iLRP (immature laminin receptor protein)为靶点的肿瘤免疫治疗,包括单克隆抗体免疫治疗和过继性细胞免疫治疗两个方向。主持完成国家自然科学基金1项,贵州省科技厅课题1项,发表文章10余篇,其中第一作者或通讯作者SCI收录10篇。

 

 

 

 

研究项目

1、国家地区基金面上项目,项目编号(81560276),治疗性iLRP单克隆抗体的抗原表位研究,2016/01-2019/1246.8万元,主持。

2国家地区基金面上项目,项目编号(81460249, 结核分枝杆菌Hsp16.3对巨噬细胞M2型极化的作用研究,2015/01-2018/1248万元,参加。

3、贵州省人力资源和社会保障厅留学人员科技活动项目经费,黔人项目资助合同(20148号,抗iLRP单抗与mLRP的免疫反应分析,2015/01-2016/12主持。

4、贵州省科技厅、遵义医学院、遵义市科技局联合基金重点项目,黔科合JLKZ[2013]02号,治疗性iLRP单克隆抗体的制备,2013/09-2016/09主持。

 

学术论文:

1.      Bainan Liu (*), Lingli Yan, Ming Zhou. Target selection of CAR T cell therapy in accordance with the TME for solid tumors. American Journal of Cancer Research. 20199(2)228-241.

2.      Bainan Liu (*), Qianqian Kong, Dong Zhang, Lingli Yan. Codon optimization significantly enhanced the expression of human 37-kDa iLRP in Escherichia coli. 3 Biotech. 2018(8): 210. (2018).

3.      Lingli Yan, Bainan Liu (*). Critical factors in chimeric antigen receptor-modified T-cell (CAR-T) therapy for solid tumors. OncoTargets and Therapy. 2019(12): 193-204. (2019).

4.      Gu Wan-Gang (*), Liu Bai-Nan (共同一作), Yuan JF. Virtual-screening targeting Human Immunodeficiency Virus type 1 integrase-lens epithelium-derived growth factor/p75 interaction for drug development. Journal of Drug Targeting. Vol. 23 (2), Feb 2015, 134-139.

5.      Weihong Tan, Bainan Liu(共同一作), Adel Barsoum, Weitao Huang, JK Kolls, Paul Schwarzenberger (*). Requirement of TPO/c-mpl for IL-17A-induced granulopoiesis and megakaryopoiesis. Journal of Leukocyte Biology. Vol. 94 (6), Dec 2013, 1303-1308.

6.      Bainan Liu (*), Wangang Gu. Immunotherapy treatments of warm autoimmune hemolytic anemia. Clinical and Developmental Immunology. Vol. 2013: 561852. September 2013.

7.      Bainan Liu, Weihong Tan, Adel Barsoum, Xiaogang Gu, Kong Chen, Weitao Huang, JK Kolls, Paul Shwarzenberger (*). IL-17 is a potent synergistic factor in enhancing DC expansion, proliferation and function with GM-CSF in mice. Experimental Hematology, Vol. 38, October 2010, 877-884.

8.      Adel L. Barsoum (*), Bainan Liu (Co-first Author), James W. Rohrer, Joseph H. Coggin, Jr., J. Allan Tucker, Lewis K. Pannell, Paul O. Schwarzenberger. Production, safety and antitumor efficacy of recombinant oncofetal Antigen/immature laminin receptor protein. Biomaterials, Vol. 30, March 2009, 3091-3099.

9.      Bainan Liu, Jianguo Tang, Jianguo Ji and Jun Gu (*). The expression of functional human parathyroid hormone in gene therapy model for osteoporosis. Cell and Tissue Research, Vol. 317, May 2004, 57-63.

10.  Bainan Liu, Jianguo Tang, Jianguo Ji and Jun Gu (*). Prevention of osteoporosis in ovariectomized mice by electroporational gene transfer of parathyroid hormone. Biotechnology Letters, Vol. 25, October 2003, 2117-2122.

 

 

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